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Mark Segal

Mark Segal

University of Florida


Dr. Segal received a B.S. degree in Biology from MIT in 1984. As an undergraduate he did research in the laboratory of Dr. Monty Krieger studying the alteration in the glycosylation pattern of a cell line defective in LDL receptor endocytosis. After graduating from MIT, Dr. Segal was accepted into the MSTP M.D./Ph.D. training program at the University of Texas Southwestern Medical School.

Research Interest

Dr. Segal's research focuses on the mechanisms of the increased cardiovascular disease in patients with diabetes, chronic kidney disease, systemic lupus erythematosus (SLE), and women who have preeclampsia or preterm delivery. His hypothesis is that a key determinate of whether an individual will develop chronic kidney disease or atherosclerosis is the ability of the individual's endothelium to tolerate their level of blood pressure, glycemia, or other stressors to the endothelium.